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| 产品编号 | KMP3416 |
|---|---|
| 产品名称 | Human TSHR Protein, His Tag |
| 产品描述 | The Human TSHR Protein(KMP3416) is produced in Insect Cells. The target gene encoding the human TSHR (NP_000360.2) (Gly21-Gly413) is expressed with a polyhistidine tag at the C-terminus. |
| 分子名称 | TSHR |
| 产品别称 | 人促甲状腺激素受体, Human TSHR Protein, His Tag, TSHR |
| 物种 | Human |
| 宿主 | Insect Cells |
| 规格 | 50ug, 100ug, 200ug |
| 纯度 | >85% as determined by SDS-PAGE |
| 纯化方式 | Affinity purification |
| 内毒素水平 | <1.0 EU/ug determined by the LAL method |
| 缓冲体系 | 50mM Tris, 150mM NaCl, 10% Glycerol, 1mM TCEP, pH7.5 |
| 产品背景 | Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis. |
| 保存条件 | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| 说明 | This product is for research use only. |
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