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产品编号 | KMH862 |
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产品名称 | Recombinant Human CEACAM8 Protein, His Tag |
产品描述 | Recombinant Human CEACAM8 Protein, His Tag (KMH862) contains the human CEACAM8(Gln35-His141) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
分子名称 | CEACAM8 |
产品别称 | CD67, CGM6, CD66b, NCA 95, CEA cell adhesion molecule 8 |
规格 | 50ug, 100ug |
物种 | Human |
宿主 | Mammalian cells |
蛋白家族 | Other protein |
编录号 | P31997 |
纯度 | ≥90% as determined by SDS-PAGE |
内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
缓冲体系 | PBS |
分子量 | 11.77 kDa |
纯化方式 | Affinity Purification |
产品背景 | Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) also known as CD66b (Cluster of Differentiation 66b), CD66b, CD67, CGM6, NCA-95, and is one of seven human CEACAM family members within the immunoglobulin superfamily. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM8 is a single chain, two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is an activation marker for human granulocytes.[1-4] |
保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |