卡梅德生物科技（天津）有限公司
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| 产品编号 | KMH647 |
|---|---|
| 产品名称 | Recombinant Human AIFM1 Protein, His Tag |
| 产品描述 | Recombinant Human AIFM1 Protein, His Tag (KMH647) contains the human AIFM1(Glu121-Asp613) was fused with the N-terminal His Tag and expressed in E. coli. |
| 分子名称 | AIFM1 |
| 产品别称 | AIF, AUNX1, CMT2D, CMTX4, COWCK, DFNX5, NADMR, NAMSD, PDCD8, COXPD6, SEMDHL, apoptosis inducing factor mitochondria associated 1 |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | E. coli |
| 蛋白家族 | Other protein |
| 编录号 | O95831 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | Please contact our customer service for more information. |
| 缓冲体系 | PBS |
| 分子量 | 54.23 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | Apoptosis-inducing factor 1, mitochondrial isoform 2 precursor, also known as AIFM1, is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. AIFM1 has been shown to cause DNA fragmentation and chromatin condensation and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression has been shown to prevent the release of AIFM1 from mitochondria, but not to block its apoptogenic activity. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Recombinant human AIFM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
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