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HAVCR2靶点

HAVCR2(Gene ID:84868)，也被称为TIM-3(T细胞免疫球蛋白和粘蛋白结构域包含蛋白3)，是一种编码主要在免疫细胞上表达的细胞表面蛋白的基因。TIM-3在调节免疫反应中起着关键作用，并与各种免疫相关疾病有关。TIM-3最初是作为T细胞表面的标记物被发现的，后来发现它在其他免疫细胞类型上也有表达，包括树突细胞和自然杀伤细胞。由于其在在T细胞衰竭和免疫耐受的背景下在免疫检查点信号传导中的作用它获得了极大的关注。TIM-3是一种免疫检查点受体，在调节T细胞反应中起着关键作用。它与其配体如半乳糖凝集素-9和磷脂酰丝氨酸(PtdSer)相互作用，传递抑制信号。T细胞上的TIM-3参与导致T细胞衰竭的过程，抑制它们的效应子功能。TIM-3与慢性感染(例如，HIV和肝炎)、癌症和自身免疫性疾病中的T细胞功能障碍和衰竭有关。在这些情况下，它对T细胞的上调导致免疫反应受损。TIM-3已经成为癌症免疫治疗的靶点。阻断TIM-3相互作用的抗体可以通过防止T细胞衰竭和促进细胞毒性T细胞活性来增强抗肿瘤免疫反应。TIM-3与多发性硬化症和类风湿性关节炎等自身免疫性疾病有关。TIM-3信号的失调会导致不受控制的免疫激活。

卡梅德生物是一家专注于生物技术领域的创新公司，致力于为科研机构、高校和公司提供高质量的HAVCR2蛋白、HAVCR2抗体等高质量的靶点产品。卡梅德生物始终秉承着客户至上的原则，致力于为科研机构、高校和公司提供最优质的HAVCR2相关产品，推动生物技术领域的不断创新和发展。

卡梅德推出的特色靶点HAVCR2蛋白产品：

编号	产品名称	物种	宿主	规格	询价
KMPH1552	Human HAVCR2/TIM3 Protein, Fc & His Tag	Human	HEK293 Cells	50ug, 100ug	询价
KMPH1553	Human HAVCR2/TIM3 Protein, His Tag	Human	HEK293 Cells	50ug, 100ug	询价
MOP1874	Mouse HAVCR2/TIM3 Protein, Fc Tag	Mouse	HEK293 Cells	50ug, 100ug	询价
MOP1875	Mouse HAVCR2/TIM3 Protein, His Tag	Mouse	HEK293 Cells	50ug, 100ug	询价
KMPH5907	Human HAVCR2/TIM3 Protein, Fc Tag	Human	HEK293 Cells	50ug, 100ug	询价
KMPH5908	Human HAVCR2/TIM3 Protein, Fc & His Tag	Human	HEK293 Cells	50ug, 100ug	询价
KMPH5909	Human HAVCR2/TIM3 Protein, Fc Tag	Human	HEK293 Cells	50ug, 100ug	询价
KMPH5910	Human HAVCR2/TIM3 Protein, Strep Tag	Human	HEK293 Cells	50ug, 100ug	询价
KMPH5911	Human HAVCR2/TIM3 Protein, Fc & His Tag	Human	HEK293 Cells	50ug, 100ug	询价
KMPH5912	Human HAVCR2/TIM3 Protein, Fc Tag	Human	HEK293 Cells	50ug, 100ug	询价
KMPH6035	Human HAVCR2/TIM3 Protein, Fc Tag	Human	HEK293 Cells	50ug, 100ug	询价
KMH513	Recombinant Human HAVCR2 Protein, His Tag	Human	Mammalian cells	50ug, 100ug	询价
MOP2174	Recombinant Mouse Havcr2/Tim-3 Protein, His Tag	Mouse	Mammalian cells	50ug, 100ug	询价
MOP2294	Recombinant Mouse TIM-3/Havcr2 Protein, His Tag	Mouse	Mammalian cells	50ug, 100ug	询价
KMH1807	Recombinant Human TIM-3/HAVCR2 C-fc Protein, Fc & His Tag	Human	Mammalian cells	50ug, 100ug	询价
MOP2295	Recombinant Mouse TIM-3/Havcr2 C-fc Protein, Fc Tag	Mouse	Mammalian cells	50ug, 100ug	询价
KMH1808	Recombinant Human TIM-3/HAVCR2 Protein, His Tag	Human	Mammalian cells	50ug, 100ug	询价
MOP2296	Recombinant Mouse TIM-3/Havcr2 Protein, His Tag	Mouse	Mammalian cells	50ug, 100ug	询价
KMP2288	Human HAVCR2 Protein, mFc Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	询价
KMP2301	Human HAVCR2 Protein, Fc Tag, Avi Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	询价
KMP2310	Cynomolgus HAVCR2 Protein, Fc Tag	Cynomolgus	HEK293 Cells	50ug, 100ug, 200ug	询价
KMP2336	Mouse HAVCR2 Protein, Fc Tag	Mouse	HEK293 Cells	50ug, 100ug, 200ug	询价
KMP2340	Mouse HAVCR2 Protein, His Tag	Mouse	HEK293 Cells	50ug, 100ug, 200ug	询价
KMP2352	Marmoset HAVCR2 Protein, His Tag	Marmoset	HEK293 Cells	50ug, 100ug, 200ug	询价
KMP2354	Mouse HAVCR2 Protein, His Tag	Mouse	HEK293 Cells	50ug, 100ug, 200ug	询价
KMP2382	Human HAVCR2 Protein, Fc Tag, His Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	询价
KMP2399	Cynomolgus HAVCR2 Protein, His Tag	Cynomolgus	HEK293 Cells	50ug, 100ug, 200ug	询价
KMP2404	Human HAVCR2 Protein, His Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	询价

卡梅德推出的特色靶点HAVCR2抗体产品：

编号	产品名称	物种	宿主	应用	规格	询价
PA7062	Rabbit Anti-Human HAVCR2 pAb	Human	Rabbit	WB, IF	50ul, 100ul	询价
PA7063	Rabbit Anti-Human HAVCR2 pAb	Human	Rabbit	IHC, IF	50ul, 100ul	询价
PA7064	Rabbit Anti-Human HAVCR2 pAb	Human	Rabbit	WB, IHC	50ul, 100ul	询价
PA10794	Rabbit Anti-Human HAVCR2 pAb	Human	Rabbit	WB	50ul, 100ul	询价
PA12960	Rabbit Anti-Human HAVCR2 pAb	Human	Rabbit	WB, IHC	50ul, 100ul	询价
PAV1688	Rabbit Anti-HAVR2/HAVCR2 Polyclonal Antibody	WB, ELISA	Rabbit	WB, ELISA	100ul	询价

卡梅德其他优势产品：

重组蛋白

病毒蛋白

细菌蛋白