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产品编号 | KMH847 |
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产品名称 | Recombinant Human CDK2 Protein, His Tag |
产品描述 | Recombinant Human CDK2 Protein, His Tag (KMH847) contains the human CDK2(Met1-Leu298) was fused with the N-terminal His Tag and expressed in E. coli. |
分子名称 | CDK2 |
产品别称 | CDKN2, p33(CDK2), cyclin dependent kinase 2 |
规格 | 50ug, 100ug |
物种 | Human |
宿主 | E. coli |
蛋白家族 | Other protein |
编录号 | P24941 |
纯度 | ≥90% as determined by SDS-PAGE |
内毒素水平 | Please contact our customer service for more information. |
缓冲体系 | PBS |
分子量 | 32.78 kDa |
纯化方式 | Affinity Purification |
产品背景 | The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. |
保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |