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产品编号 | MOP2235 |
---|---|
产品名称 | Recombinant Mouse OX40/Tnfsf4 Protein, Fc Tag |
产品描述 | Recombinant Mouse OX40/Tnfsf4 Protein, Fc Tag (MOP2235) contains the mouse Tnfrsf4(Val20-Pro211) was fused with the N-terminal Fc Tag and expressed in Mammalian cells. |
分子名称 | Tnfrsf4 |
产品别称 | Ox40, ACT35, CD134, Ly 70, Txgp1, TXGP1L, tumor necrosis factor receptor superfamily, member 4 |
规格 | 50ug, 100ug |
物种 | Mouse |
宿主 | Mammalian cells |
蛋白家族 | Other protein |
编录号 | P47741 |
纯度 | ≥90% as determined by SDS-PAGE |
内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
缓冲体系 | PBS |
分子量 | 46.12 kDa |
纯化方式 | Affinity Purification |
产品背景 | OX4L, a member of the TNF superfamily of structurally related proteins, exists primarily as a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells (APCs), such as dendritic cells and activated B-cells, and also on various other cells such as vascular endothelial cells, mast cells, and natural killer cells. OX4L signals specifically through the OX4 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX4/OX4L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. |
保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |